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Organic Acid-Base



 

Organic Base: 

        Organic bases are usually, but not always, proton acceptors. They usually contain nitrogen atoms, which can easily be protonated. Amines and nitrogen-containing heterocyclic compounds are organic bases. Examples include:


Pyridine,  Methyl amine, Imidazole, Benzimidazole, Histidine, Phosphazene bases, Hydroxides of some organic cations



Hydroxide donors:  

        Some organic bases, such as tetramethylammonium hydroxide, tetrabutylammonium hydroxide, or choline hydroxide are hydroxide donors rather than proton acceptors like the above compounds. 




 

 

Organic Acid: 

        An organic acid is an organic compound with acidic properties. The most common organic acids are the carboxylic acids, whose acidity is associated with their carboxyl group –COOH. Sulfonic acids, containing the group –SO2OH, are relatively stronger acids. Alcohols, with –OH, can act as acids but they are usually very weak. The relative stability of the conjugate base of the acid determines its acidity. Other groups can also confer acidity, usually weakly: the thiol group –SH, the enol group, and the phenol group. In biological systems, organic compounds containing these groups are generally referred to as organic acids.





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